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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR5A2
All Species:
22.73
Human Site:
S280
Identified Species:
38.46
UniProt:
O00482
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00482
NP_003813.1
541
61331
S280
Y
P
D
P
Y
T
S
S
P
E
S
I
M
G
Y
Chimpanzee
Pan troglodytes
XP_520248
771
84677
P514
Y
P
E
P
Y
A
S
P
P
Q
P
G
L
P
Y
Rhesus Macaque
Macaca mulatta
XP_001110281
541
61327
S280
Y
P
D
P
Y
T
S
S
P
E
S
I
M
G
Y
Dog
Lupus familis
XP_547371
548
62005
S287
Y
P
D
P
Y
T
S
S
P
E
S
I
M
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
P45448
560
64002
S299
Y
P
D
P
Y
S
S
S
P
E
S
M
M
G
Y
Rat
Rattus norvegicus
Q9QWM1
560
63886
S299
Y
P
D
P
Y
S
S
S
P
E
S
M
M
G
Y
Wallaby
Macropus eugenll
Q95L87
463
51850
D238
K
L
L
Q
L
E
P
D
E
G
Q
L
K
A
R
Platypus
Ornith. anatinus
XP_001505652
637
72367
S376
Y
P
D
P
Y
T
S
S
P
E
S
I
M
G
Y
Chicken
Gallus gallus
O42101
501
57084
L268
I
P
H
L
I
L
E
L
Q
K
C
E
P
D
E
Frog
Xenopus laevis
P70033
435
49986
Q211
Q
S
H
T
L
I
N
Q
L
L
T
A
E
D
I
Zebra Danio
Brachydanio rerio
Q9PU65
477
54037
I253
P
L
G
T
P
M
L
I
E
D
G
Y
R
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33244
1027
108400
A768
I
G
S
L
Q
N
T
A
D
S
K
L
C
F
D
Honey Bee
Apis mellifera
XP_001122182
878
92065
G624
S
P
K
A
F
N
F
G
E
Q
S
T
Q
S
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791919
487
54933
L261
T
P
K
L
I
Q
E
L
I
R
S
E
P
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
99.6
88.1
N.A.
86.9
86.9
57.4
80.6
90
23.6
27.5
N.A.
26.1
28.2
N.A.
45.4
Protein Similarity:
100
52.1
99.8
89.7
N.A.
90.3
90.5
67.8
83
91.1
41.2
44.7
N.A.
35.8
40.2
N.A.
61
P-Site Identity:
100
46.6
100
100
N.A.
86.6
86.6
0
100
6.6
0
0
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
6.6
100
13.3
13.3
6.6
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% C
% Asp:
0
0
43
0
0
0
0
8
8
8
0
0
0
22
8
% D
% Glu:
0
0
8
0
0
8
15
0
22
43
0
15
8
0
8
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
0
0
0
0
8
0
8
8
8
0
43
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
15
0
0
0
15
8
0
8
8
0
0
29
0
0
8
% I
% Lys:
8
0
15
0
0
0
0
0
0
8
8
0
8
0
0
% K
% Leu:
0
15
8
22
15
8
8
15
8
8
0
15
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
15
43
0
0
% M
% Asn:
0
0
0
0
0
15
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
72
0
50
8
0
8
8
50
0
8
0
15
8
0
% P
% Gln:
8
0
0
8
8
8
0
8
8
15
8
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% R
% Ser:
8
8
8
0
0
15
50
43
0
8
58
0
0
8
0
% S
% Thr:
8
0
0
15
0
29
8
0
0
0
8
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
0
50
0
0
0
0
0
0
8
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _